Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705846 | 0.85 | HSD11B1 (0.49) | MAPK1ALDH1A1POLBMAPTCES1 | |
| SCHEMBL10965853 | 0.83 | MAPK1 (0.46) | MAPK1ALDH1A1POLBMAPTCES1 | |
| SCHEMBL1625677 | 0.80 | MAOB (0.47) | MAPK1ALDH1A1POLBMAPTMAOB | |
| SCHEMBL1647740 | 0.78 | MAPK1 (0.55) | MAPK1ALDH1A1POLBMAPTCES1 | |
| SCHEMBL7019649 | 0.77 | ALDH1A1 (0.52) | MAPK1ALDH1A1POLBMAPTCES1 | |
| SCHEMBL416522 | 0.77 | ESR1 (0.52) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27847800 | 0.77 | MAPK1 (0.63) | MAPK1ALDH1A1MAPTCES1LMNA | |
| SCHEMBL3530965 | 0.76 | ALDH1A1 (0.51) | MAPK1ALDH1A1POLBMAPTCES1 | |
| SCHEMBL28359072 | 0.76 | ALDH1A1 (0.51) | MAPK1ALDH1A1POLBMAPTCES1 | |
| SCHEMBL6262303 | 0.76 | CA1 (0.53) | MAPK1ALDH1A1POLBMAPTCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |