Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15876051 | 0.89 | FPR3 (0.48) | FPR3FPR2SMN1; SMN2MAPTKMT2A | |
| SCHEMBL6368466 | 0.85 | FPR3 (0.44) | FPR3FPR2GRK2SMN1; SMN2MAPT | |
| SCHEMBL3763507 | 0.82 | VSIR (0.53) | FPR3FPR2MAPTMAPK1KMT2A | |
| SCHEMBL12121617 | 0.82 | MAPT (0.55) | GRK2MAPTHPGDKMT2ALMNA | |
| SCHEMBL7429994 | 0.82 | CASR (0.52) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL24077532 | 0.81 | ALDH1A1 (0.53) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL4119738 | 0.81 | ALDH1A1 (0.47) | FPR3FPR2SMN1; SMN2MAPTHDAC4 | |
| SCHEMBL1433839 | 0.81 | MEN1 (0.47) | FPR3FPR2GRK2SMN1; SMN2MAPT | |
| SCHEMBL14065391 | 0.81 | HDAC3 (0.46) | FPR3FPR2SMN1; SMN2MAPTHDAC3 | |
| SCHEMBL30936914 | 0.81 | FPR3 (0.48) | FPR3FPR2GRK2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019051207-A1 | ANALOGS OF PROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) AGONISTS AND METHODS OF USING THE SAME | THE UNIVERSITY OF TOLEDO (US) | 2019-03-14 | — | — | WO | disclosed |