Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.41 |
| ▸ | PRKCG | P05129 | 3/20 | 0.41 |
| ▸ | PRKCB | P05771 | 3/20 | 0.41 |
| ▸ | PRKCH | P24723 | 3/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GSTA2 | P09210 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.36 |
| ▸ | GSTM1 | P09488 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893349 | 0.79 | POLB (0.42) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL1333553 | 0.79 | POLB (0.42) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL52102 | 0.79 | POLB (0.42) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL18219141 | 0.69 | POLB (0.37) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL12546111 | 0.69 | POLB (0.37) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL15457672 | 0.69 | POLB (0.37) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL9496285 | 0.66 | ALDH1A1 (0.38) | PRKCAALDH1A1 | |
| SCHEMBL10777104 | 0.63 | POLB (0.40) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Hexane SCHEMBL3428301 | 0.62 | ALDH1A1 (0.62) | ALDH1A1CES2 | |
| Hexane SCHEMBL849892 | 0.62 | ALDH1A1 (0.62) | ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10226456-B2 | Methods and compositions for preventing opioid abuse | 3ST RESEARCH LLC (US) | 2019-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10226456-B2 | Methods and compositions for preventing opioid abuse | OPRM1, OPRK1, OPRD1 | PRKCA 3337/4885PRKD3 4454/4885PRKCG 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.