Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 4/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16353467 | 0.78 | SLC6A1 (0.44) | SLC6A11SLC6A1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL22960803 | 0.78 | HDAC6 (0.44) | SLC6A11SLC6A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3931384 | 0.77 | SLC6A11 (0.48) | SLC6A11SLC6A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20799447 | 0.76 | ALDH1A1 (0.50) | SLC6A11SLC6A1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23777331 | 0.75 | SLC6A11 (0.47) | SLC6A11SLC6A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16557240 | 0.75 | HDAC6 (0.48) | SLC6A11SLC6A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16218326 | 0.75 | HDAC6 (0.48) | SLC6A11SLC6A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16639379 | 0.75 | HDAC6 (0.45) | SLC6A11SLC6A1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4066783 | 0.73 | SLC6A11 (0.51) | SLC6A11SLC6A1KMT2AMEN1TP53 | |
| SCHEMBL30861823 | 0.73 | SLC6A11 (0.53) | SLC6A11SLC6A1KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10519446-B2 | Organic compounds to treat hepatitis B virus | NOVARTIS AG (CH) | 2019-12-31 | — | — | US | disclosed |