Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20799489 | 0.87 | ALDH1A1 (0.53) | L3MBTL1KMT2AATMALDH1A1MAPT | |
| SCHEMBL17384693 | 0.82 | LMNA (0.52) | L3MBTL1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL20799483 | 0.80 | ALDH1A1 (0.50) | L3MBTL1KMT2AATMALDH1A1MAPT | |
| SCHEMBL18987868 | 0.74 | MAOB (0.51) | L3MBTL1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL5553780 | 0.74 | MGAM (0.51) | L3MBTL1KMT2AATMALDH1A1MAPT | |
| SCHEMBL20799492 | 0.73 | MAOB (0.47) | L3MBTL1KMT2AALDH1A1MAPTHPGD | |
| Hydrogen Sulfide SCHEMBL28775857 | 0.73 | MGAM (0.50) | L3MBTL1KMT2AATMALDH1A1MAPT | |
| SCHEMBL19020788 | 0.72 | KDM4E (0.49) | L3MBTL1KMT2AATMALDH1A1MAPT | |
| Urea SCHEMBL6016094 | 0.71 | MGAM (0.47) | KMT2AALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL11997780 | 0.70 | PDGFRB (0.47) | L3MBTL1KMT2AATMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | ABL1, FLT3, MAP3K7 | L3MBTL1 4664/4885KMT2A 870/4885ATM 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.