Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | OGA | O60502 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18987868 | 0.92 | MAOB (0.51) | LMNAMAOBMAPTRAB9ATSHR | |
| SCHEMBL20799483 | 0.85 | ALDH1A1 (0.50) | LMNATDP1MAPTRAB9ATSHR | |
| SCHEMBL20799494 | 0.82 | L3MBTL1 (0.47) | LMNATDP1OGAMAPTRAB9A | |
| SCHEMBL20799489 | 0.81 | ALDH1A1 (0.53) | LMNATDP1MAPTRAB9AL3MBTL1 | |
| SCHEMBL20799492 | 0.80 | MAOB (0.47) | LMNAMAOBMAPTRAB9ATSHR | |
| SCHEMBL4027801 | 0.79 | RAB9A (0.57) | LMNASIRT2SIRT1SIRT3OGA | |
| SCHEMBL7227312 | 0.79 | MAOB (0.54) | LMNAMAOBMAPTRAB9ATSHR | |
| SCHEMBL5553780 | 0.78 | MGAM (0.51) | LMNATDP1MAPTRAB9AL3MBTL1 | |
| SCHEMBL20474252 | 0.78 | PDGFRB (0.73) | MAOBMAPTRAB9ANPC1PDGFRB | |
| SCHEMBL6862895 | 0.77 | LMNA (0.54) | LMNATDP1SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015198349-A1 | A ONE POT SYNTHESIS OF 3-SUBSTITUTED QUINOLINE CARBOXYLATES AND ITS DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-30 | — | — | WO | disclosed |