Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 14/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379844 | 0.75 | KDM4E (0.48) | KDM4EPOLBATM | |
| SCHEMBL11037099 | 0.75 | GRIN2B (0.59) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL11037096 | 0.72 | GRIN2B (0.56) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL16702044 | 0.72 | GRIN2B (0.65) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL456941 | 0.71 | GRIN2B (1.00) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL17196594 | 0.71 | GRIN2B (1.00) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL20675953 | 0.69 | NOS2 (0.96) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL14291059 | 0.69 | NOS2 (0.96) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL45769 | 0.68 | GRIN2B (0.68) | GRIN2BGRIN1NOS2SIGMAR1GRIN2D | |
| SCHEMBL704708 | 0.67 | KDM4E (0.62) | KDM4EPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573559-B1 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC (US) | 2019-03-13 | — | — | EP | disclosed |