SCHEMBL20809342

SCHEMBL20809342

Cc1cccc(-c2nccc3cc(CC(C)(C)C)ccc23)c1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 9/20 0.39
SCN9A Q15858 3/20 0.39
KMO O15229 1/20 0.36
ROCK1 Q13464 2/20 0.35
NPC1 O15118 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
DPP4 P27487 1/20 0.34
BCHE P06276 1/20 0.34
PDE10A Q9Y233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809339 0.89 SCN9A (0.41) SCN9AROCK1
SCHEMBL20809368 0.88 MAPK14 (0.38) MAPK14SCN9AKMOROCK1NPC1
SCHEMBL20809338 0.87 SCN9A (0.41) SCN9AROCK1NPC1MAPK1RAB9A
SCHEMBL25443604 0.82 SCN9A (0.38) SCN9AROCK1
SCHEMBL20809425 0.82 MAPK14 (0.39) MAPK14SCN9AKMOROCK1NPC1
SCHEMBL30037967 0.81 SCN9A (0.35) SCN9AROCK1
SCHEMBL25776343 0.80 ROCK1 (0.37) SCN9AROCK1
SCHEMBL20809345 0.80 GRIN1 (0.35) MAPK14NPC1TSHRMAPK1RAB9A
SCHEMBL25443559 0.79 SCN9A (0.40) SCN9AROCK1TSHRMAPK1SMN1; SMN2
SCHEMBL24795591 0.79 MEN1 (0.36) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 MAPK14 3666/4885SCN9A 3462/4885KMO 597/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 MAPK14 3666/4885SCN9A 3462/4885KMO 597/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 MAPK14 3551/4885SCN9A 3256/4885KMO 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.