SCHEMBL20810453

SCHEMBL20810453

O=Nc1cc(-c2oc3cccc(N=O)c3c(=O)c2O)ccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 12/20 0.51
KMT2A Q03164 12/20 0.51
KDM4E B2RXH2 9/20 0.51
CYP3A4 P08684 9/20 0.51
MAPT P10636 9/20 0.51
HSD17B10 Q99714 8/20 0.51
ALOX15 P16050 7/20 0.51
CYP2C9 P11712 7/20 0.51
TP53 P04637 6/20 0.51
HPGD P15428 6/20 0.51
RECQL P46063 5/20 0.51
CYP2D6 P10635 5/20 0.51
CYP2C19 P33261 5/20 0.51
LMNA P02545 5/20 0.51
MAPK1 P28482 4/20 0.51
USP2 O75604 3/20 0.51
AMY1A P0DUB6 3/20 0.51
ALOX12 P18054 3/20 0.51
CDK2 P24941 3/20 0.51
PIM1 P11309 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22625755 0.92 MEN1 (0.61) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL13964377 0.78 MEN1 (0.74) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL18676308 0.76 MEN1 (0.72) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL31326068 0.76 MEN1 (0.72) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL29826664 0.76 MEN1 (0.72) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL13076536 0.74 MEN1 (0.73) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL21347799 0.73 MEN1 (0.74) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL25761542 0.71 MEN1 (0.59) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL13458641 0.70 MEN1 (0.58) MEN1KMT2AKDM4ECYP3A4MAPT
SCHEMBL7660030 0.70 NOX4 (0.76) MEN1KMT2AKDM4ECYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3453766-A1 METHOD FOR PRODUCING FLAVONOID CLATHRATE Taiyo Kagaku Co., Ltd. (JP) 2019-03-13 EP disclosed