SCHEMBL22625755

SCHEMBL22625755

O=Nc1cccc2oc(-c3ccc(O)c(O)c3)c(O)c(=O)c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.61
KMT2A Q03164 8/20 0.61
KDM4E B2RXH2 7/20 0.61
ALOX15 P16050 6/20 0.61
CYP3A4 P08684 6/20 0.61
HSD17B10 Q99714 6/20 0.61
MAPT P10636 6/20 0.61
RECQL P46063 5/20 0.61
TP53 P04637 5/20 0.61
CYP2C9 P11712 4/20 0.61
MAPK1 P28482 4/20 0.61
AMY1A P0DUB6 3/20 0.61
ALOX12 P18054 3/20 0.61
CDK2 P24941 3/20 0.61
PIM1 P11309 2/20 0.61
CD38 P28907 2/20 0.61
CYP2D6 P10635 2/20 0.61
CYP2C19 P33261 2/20 0.61
ST6GAL1 P15907 1/20 0.61
BCL9 O00512 5/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20810453 0.92 MEN1 (0.51) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL13964377 0.86 MEN1 (0.74) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL18676308 0.85 MEN1 (0.72) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL29826664 0.85 MEN1 (0.72) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL31326068 0.85 MEN1 (0.72) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL4879748 0.79 AMY1A (0.78) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL7660030 0.78 NOX4 (0.76) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL13076536 0.76 MEN1 (0.73) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL169366 0.76 MEN1 (1.00) MEN1KMT2AKDM4EALOX15CYP3A4
SCHEMBL15676575 0.76 MEN1 (1.00) MEN1KMT2AKDM4EALOX15CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3733860-A1 FLAVONOID INCLUSION COMPOUNDS Taiyo Kagaku Co., Ltd. (JP) 2020-11-04 EP disclosed