Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20995348 | 0.89 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL20995373 | 0.86 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL14212098 | 0.81 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL20995383 | 0.81 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL20812240 | 0.81 | PTGS2 (0.47) | HSP90AA1HSP90AB1NPC1RAB9APTGS2 | |
| SCHEMBL25494292 | 0.81 | FLT3 (0.46) | MEN1KMT2ANPC1RAB9APTGS2 | |
| SCHEMBL26156421 | 0.79 | CYP19A1 (0.45) | NPC1RAB9APTGS2PTGS1ALDH1A3 | |
| SCHEMBL13036563 | 0.79 | CYP19A1 (0.47) | KMT2ANPC1RAB9APTGS2PTGS1 | |
| SCHEMBL27757262 | 0.78 | NPC1 (0.52) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL18922484 | 0.78 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Theraprutics, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | GCGR, STUB1, GID4 | HSP90AA1 1424/4885HSP90AB1 1796/4885MEN1 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.