SCHEMBL25494292

SCHEMBL25494292

Cc1ccc(-c2cn(C(C)(C)C)nn2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FLT3 P36888 1/20 0.46
▸ SRC P12931 5/20 0.45
▸ NPC1 O15118 5/20 0.44
▸ RAB9A P51151 5/20 0.44
▸ PTGS2 P35354 3/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ KMT2A Q03164 3/20 0.44
▸ PTGS1 P23219 1/20 0.44
▸ CA12 O43570 2/20 0.43
▸ CA1 P00915 2/20 0.43
▸ CA2 P00918 2/20 0.43
▸ CA9 Q16790 2/20 0.43
▸ CA5A P35218 1/20 0.43
▸ CA5B Q9Y2D0 1/20 0.43
▸ KDR P35968 2/20 0.42
▸ EPHB4 P54760 2/20 0.42
▸ TEK Q02763 2/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ ALDH1A3 P47895 1/20 0.41
▸ ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20995390 0.87 FLT3 (0.45) FLT3SRCNPC1RAB9APTGS2
SCHEMBL27757262 0.86 NPC1 (0.52) FLT3SRCNPC1RAB9APTGS2
SCHEMBL20812240 0.85 PTGS2 (0.47) FLT3NPC1RAB9APTGS2PTGS1
SCHEMBL20995384 0.84 NPC1 (0.44) FLT3SRCNPC1RAB9APTGS2
SCHEMBL26156421 0.84 CYP19A1 (0.45) SRCNPC1RAB9APTGS2PTGS1
SCHEMBL13036563 0.83 CYP19A1 (0.47) NPC1RAB9APTGS2KMT2APTGS1
SCHEMBL20995347 0.82 FLT3 (0.41) FLT3SRCNPC1RAB9APTGS2
SCHEMBL20812238 0.81 HSP90AA1 (0.55) NPC1RAB9APTGS2MEN1KMT2A
SCHEMBL22530587 0.78 P2RY14 (0.49) SRCNPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL14212098 0.76 HSP90AA1 (0.39) NPC1RAB9APTGS2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 — — US disclosed
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 — — US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 — — US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 — — US disclosed
US-20230167149-A1 CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS GLYCOMIMETICS, INC. (US) 2023-06-01 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R FLT3 873/4885SRC 1366/4885NPC1 652/4885
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A FLT3 921/4885SRC 1129/4885NPC1 2429/4885
US-20230167149-A1 CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS SIGLEC7, SIGLEC9, ASGR1 FLT3 21/4885SRC 505/4885NPC1 915/4885
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, ASGR1, FCGR3B FLT3 995/4885SRC 412/4885NPC1 1454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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