Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24015444 | 0.79 | ALDH1A1 (0.42) | ALDH1A1BCHEHIF1A | |
| SCHEMBL24065129 | 0.77 | ALDH1A1 (0.40) | ALDH1A1BCHEHIF1A | |
| SCHEMBL24067438 | 0.75 | TRPM8 (0.43) | ALDH1A1BCHEHIF1A | |
| SCHEMBL14600549 | 0.74 | ALDH1A1 (0.42) | ALDH1A1BCHEHIF1A | |
| SCHEMBL25670652 | 0.71 | ALDH1A1 (0.36) | ALDH1A1BCHEHIF1A | |
| SCHEMBL22045458 | 0.69 | ALDH1A1 (0.42) | ALDH1A1BCHEHIF1A | |
| SCHEMBL24064975 | 0.67 | ALDH1A1 (0.36) | ALDH1A1BCHEHIF1A | |
| SCHEMBL11023549 | 0.62 | ALDH1A1 (0.53) | ALDH1A1BCHEHIF1A | |
| SCHEMBL22388992 | 0.62 | ALDH1A1 (0.36) | ALDH1A1BCHEHIF1A | |
| SCHEMBL4336527 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327882-A2 | ENPP1 INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER | The Board of Trustees of the Leland Stanford Junior University (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2023077083-A1 | ENPP1 INHIBITORS AS INHIBITORS OF METASTASIS | ANGARUS THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2019051269-A1 | ENPP1 INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-03-14 | — | — | WO | disclosed |