Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24064975 | 0.88 | ALDH1A1 (0.36) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL24067438 | 0.77 | TRPM8 (0.43) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL23900903 | 0.75 | FDPS (0.38) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL25670652 | 0.73 | ALDH1A1 (0.36) | ALDH1A1BCHEHIF1A | |
| SCHEMBL14600549 | 0.70 | ALDH1A1 (0.42) | ALDH1A1BCHEHIF1A | |
| SCHEMBL22045458 | 0.70 | ALDH1A1 (0.42) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL24015444 | 0.70 | ALDH1A1 (0.42) | ALDH1A1BCHEHIF1A | |
| SCHEMBL10535781 | 0.69 | — | — | |
| SCHEMBL22388992 | 0.69 | ALDH1A1 (0.36) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL11618959 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369855-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369855-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | CD4, MCL1, CCNB1 | ALDH1A1 1130/4885BCHE 675/4885HIF1A 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.