Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24872350 | 0.88 | TRPM8 (0.38) | TRPM8 | |
| SCHEMBL22045458 | 0.85 | ALDH1A1 (0.42) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL22199556 | 0.77 | TRPM8 (0.31) | TRPM8 | |
| SCHEMBL24245855 | 0.73 | ALDH1A1 (0.40) | ALDH1A1BCHEHIF1A | |
| SCHEMBL22199555 | 0.70 | MMP1 (0.35) | TRPM8 | |
| SCHEMBL24065129 | 0.69 | ALDH1A1 (0.40) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL24067438 | 0.67 | TRPM8 (0.43) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL21787980 | 0.67 | ALDH1A1 (0.39) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL8817046 | 0.67 | ALDH1A1 (0.39) | ALDH1A1BCHEHIF1ATRPM8 | |
| SCHEMBL6245732 | 0.66 | MMP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210169896-A1 | A CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-06-10 | — | — | US | disclosed |
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210169896-A1 | A CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES | PBDC1, BRD2, CD79B | ALDH1A1 2260/4885BCHE 1176/4885HIF1A 3188/4885 |
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | TEKT1, TEK, BTN3A1 | ALDH1A1 4604/4885BCHE 2187/4885HIF1A 3596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.