Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889302 | 0.98 | LIPG (0.54) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL7899209 | 0.98 | LIPG (0.54) | LIPGALOX5PTGS2BIDMCL1 | |
| Iodide SCHEMBL8515618 | 0.97 | LIPG (0.53) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL4768903 | 0.95 | LIPG (0.44) | LIPGKMT2ATLR8MEN1NR1I2 | |
| SCHEMBL7896315 | 0.87 | KMT2A (0.42) | LIPGKMT2ALMNACYP3A4MAPT | |
| SCHEMBL16634789 | 0.85 | ALOX5 (0.54) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL5815657 | 0.84 | LIPG (0.53) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL2453233 | 0.84 | LIPG (0.53) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL10384517 | 0.82 | LIPG (0.51) | LIPGALOX5PTGS2BIDMCL1 | |
| SCHEMBL9456052 | 0.82 | LIPG (0.56) | LIPGBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801861-B2 | Antimicrobial substituted thiazoles and methods of use | PURDUE RESEARCH FOUNDATION (US) | 2017-10-31 | — | — | US | disclosed |
| US-20160243088-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2016-08-25 | — | — | US | disclosed |
| US-9353072-B2 | Antimicrobial substituted thiazoles and methods of use | PURDUE RESEARCH FOUNDATION (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140121249-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | PURDUE RESEARCH FOUNDATION | 2014-05-01 | — | — | US | disclosed |
| US-8158674-B2 | Chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110166366-A1 | Novel Chalcogenoxanthylium Dyes for Purging Blood Pathogens and for Photodynamic Therapy | DETTY MICHAEL R | 2011-07-07 | — | — | US | disclosed |
| US-7906500-B2 | Chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-03-15 | — | — | US | disclosed |
| WO-2006026033-A2 | NOVEL CHALCOGENOXANTHYLIUM DYES FOR PURGING BLOOD PATHOGENS AND FOR PHOTODYNAMIC THERAPY | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK STOR (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060040908-A1 | Novel chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | NIH-DEITR | 2006-02-23 | — | — | US | disclosed |
| EP-0441718-A1 | Herbicidally active triazolopyridine compounds | RHONE-POULENC AGROCHIMIE (FR) | 1991-08-14 | — | — | EP | disclosed |
| CN-1053792-A | Herbicidal compound with triazolopyridine group | RHONE POULENO AGROCHIMIE (FR) | 1991-08-14 | — | — | CN | disclosed |
| US-4055665-A | Treating arrythmia with phenylthioaralkylamines | MERCK & CO., INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4018830-A | Phenylthioaralkylamines | MERCK & CO., INC. (US) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166366-A1 | Novel Chalcogenoxanthylium Dyes for Purging Blood Pathogens and for Photodynamic Therapy | ABCB1, ABCC1, GSTP1 | LIPG 24/4885ALOX5 1027/4885PTGS2 210/4885 |
| US-20060040908-A1 | Novel chalcogenoxanthylium dyes for purging blood pathogens and for photodynamic therapy | ABCB1, ABCC1, GSTP1 | LIPG 24/4885ALOX5 1027/4885PTGS2 210/4885 |
| US-20140121249-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | CLPP, ELANE, NOD2 | LIPG 2909/4885ALOX5 1925/4885PTGS2 2099/4885 |
| US-20160243088-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | CLPP, ELANE, NOD2 | LIPG 2909/4885ALOX5 1925/4885PTGS2 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.