Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20816045 | 0.83 | LMNA (0.47) | METPOLBLMNANOS2MAPT | |
| SCHEMBL20816043 | 0.70 | OPRM1 (0.47) | LMNANPC1RAB9AMAPTKMT2A | |
| SCHEMBL12393140 | 0.68 | KDM4E (0.46) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20816037 | 0.67 | PTGS2 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22300409 | 0.66 | MEN1 (0.50) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1156585 | 0.65 | FBP1 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2134855 | 0.64 | CA2 (0.48) | GPR183LMNAKMT2ANOD2NOD1 | |
| SCHEMBL10125216 | 0.64 | POLB (0.45) | POLBLMNAGAAMAPTKMT2A | |
| SCHEMBL9414075 | 0.62 | CA12 (0.66) | METHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9414072 | 0.62 | CA12 (0.66) | METHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577371-B2 | Small molecule histone methyltransferase SUV39H1 inhibitor and uses thereof | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2020-03-03 | — | — | US | disclosed |
| US-20190084987-A1 | Small Molecule Histone Methyltransferase SUV39H1 Inhibitor and Uses Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10577371-B2 | Small molecule histone methyltransferase SUV39H1 inhibitor and uses thereof | SUV39H2, SUV39H1, EZH1 | MET 1681/4885POLB 1730/4885HDAC3 79/4885 |
| US-20190084987-A1 | Small Molecule Histone Methyltransferase SUV39H1 Inhibitor and Uses Thereof | SUV39H2, SUV39H1, EZH1 | MET 1681/4885POLB 1730/4885HDAC3 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.