Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KDM6B | O15054 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28426901 | 0.82 | KDM5B (0.57) | KDM5BKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL1709275 | 0.76 | CFD (0.57) | KDM5BKDM4EKMT2AAPEX1ALDH1A1 | |
| SCHEMBL28014585 | 0.69 | DHODH (0.54) | KMT2AALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL14399061 | 0.67 | AGTR1 (0.55) | KDM5BKDM4EKDM6BKDM4AKDM4D | |
| SCHEMBL11082890 | 0.67 | SMN1; SMN2 (0.63) | KDM4EKMT2AALDH1A1POLBHPGD | |
| SCHEMBL4017043 | 0.66 | HCAR2 (0.45) | KDM5BKDM6BKDM4AKDM4DKDM4C | |
| SCHEMBL28398432 | 0.66 | KCNN4 (0.39) | KDM5BKDM4EKDM4CKMT2AALDH1A1 | |
| SCHEMBL22534331 | 0.65 | KDM5B (0.46) | KDM5BKDM6BKDM4AKDM4DKDM4C | |
| SCHEMBL28433433 | 0.64 | HCAR3 (0.37) | KDM5BKDM4EKDM6BKDM4CKMT2A | |
| SCHEMBL25351331 | 0.64 | KDM4E (0.50) | KDM5BKDM4EKDM6BKDM4AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |