Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20791050 | 0.90 | ALDH1A1 (0.37) | CNR2ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL3648987 | 0.85 | SMN1; SMN2 (0.41) | CNR2ALDH1A1SMN1; SMN2LMNAKCNN4 | |
| SCHEMBL2060134 | 0.76 | CNR2 (0.52) | CNR2LMNAMAOBF2F10 | |
| SCHEMBL3923273 | 0.75 | CNR2 (0.51) | CNR2MAOBPIN1 | |
| SCHEMBL7040767 | 0.74 | CNR2 (0.39) | CNR2MAOBF2F10PLG | |
| SCHEMBL11937216 | 0.74 | LMNA (0.49) | ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL13860067 | 0.74 | MMP8 (0.43) | ALDH1A1SMN1; SMN2TSHRHTT | |
| SCHEMBL20790639 | 0.74 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL421400 | 0.74 | CNR2 (0.47) | CNR2ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL3654667 | 0.74 | ALDH1A1 (0.39) | CNR2ALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055590-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. (US) | 2019-03-21 | — | — | WO | disclosed |