Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040568 | 0.76 | CNR2 (0.33) | CNR2MAPTMAPK1 | |
| SCHEMBL20826480 | 0.74 | CNR2 (0.41) | CNR2F2F10PLGPRSS1 | |
| SCHEMBL8484338 | 0.68 | PIN1 (0.34) | MAPTALOX15MAPK1HSD17B10 | |
| SCHEMBL10228098 | 0.68 | CNR2 (0.51) | CNR2MAPK1F2F10PLG | |
| SCHEMBL7045044 | 0.66 | RORC (0.38) | CNR2MAPTF2F10PLG | |
| SCHEMBL7154295 | 0.66 | GAA (0.33) | CNR2MAPTMAPK1 | |
| SCHEMBL20791050 | 0.65 | ALDH1A1 (0.37) | CNR2MAPT | |
| SCHEMBL6279399 | 0.64 | CNR2 (0.58) | CNR2MAPTF2F10PLG | |
| SCHEMBL22992388 | 0.64 | CNR2 (0.48) | CNR2MAPTHSD17B10F2F10 | |
| SCHEMBL25174839 | 0.64 | CNR2 (0.48) | CNR2MAPK1F2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956286-B1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6147217-A | Synthesis of terfenadine and derivatives | SEPRACOR INC. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0956286-A1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR, INC. (US) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998033789-A1 | SYNTHESIS OF TERFENADINE AND DERIVATIVES | SEPRACOR, INC. (US) | 1998-08-06 | — | — | WO | disclosed |