Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 7/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828083 | 1.00 | CAPN1 (0.49) | CAPN1CTSBCTSKKISS1RCTSL | |
| SCHEMBL20827981 | 0.95 | NPY4R (0.52) | CAPN1CTSBCTSKNPY1RNPY2R | |
| SCHEMBL20828093 | 0.95 | NPY4R (0.52) | CAPN1CTSBCTSKNPY1RNPY2R | |
| SCHEMBL20828106 | 0.95 | NPY4R (0.52) | CAPN1CTSBCTSKNPY1RNPY2R | |
| SCHEMBL20827929 | 0.95 | NPY4R (0.52) | CAPN1CTSBCTSKNPY1RNPY2R | |
| SCHEMBL20827990 | 0.92 | CAPN1 (0.56) | CAPN1CTSBCTSKCTSLCTSS | |
| SCHEMBL20827853 | 0.92 | CAPN1 (0.56) | CAPN1CTSBCTSKCTSLCTSS | |
| SCHEMBL20816886 | 0.91 | KISS1R (0.48) | KISS1RNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL20816889 | 0.91 | KISS1R (0.48) | KISS1RNPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL20816887 | 0.91 | KISS1R (0.48) | KISS1RNPY1RNPY2RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190085024-A1 | Alpha-Ketoamide Inhibitors Of Cysteine Proteases | Phelix Therapeutics (US) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190085024-A1 | Alpha-Ketoamide Inhibitors Of Cysteine Proteases | CTSS, CTSB, CTSL | CAPN1 8/4885CTSB 2/4885CTSK 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.