Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828385 | 0.84 | MAPT (0.54) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL25422781 | 0.76 | SLCO1B1 (0.39) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL20828343 | 0.75 | DGAT1 (0.42) | ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL2830733 | 0.73 | ICAM1 (0.44) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3522758 | 0.69 | MEN1 (0.35) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL30664608 | 0.67 | MAPT (0.43) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL26655880 | 0.67 | MAPT (0.43) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL15244567 | 0.66 | KDM4C (0.37) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL21058017 | 0.66 | GABRA5 (0.40) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16979834 | 0.66 | KDM4C (0.49) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |