Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20820817 | 0.79 | DGAT1 (0.50) | DGAT1SLC2A1ABL1THRBHDAC6 | |
| SCHEMBL20828341 | 0.75 | DGAT1 (0.48) | DGAT1NPC1RAB9ASMN1; SMN2SLC2A1 | |
| SCHEMBL20828342 | 0.75 | DGAT1 (0.58) | DGAT1SLC2A1HDAC6ALDH1A1MCHR1 | |
| SCHEMBL20828386 | 0.75 | ALDH1A1 (0.39) | NPC1LMNARAB9AALDH1A1 | |
| SCHEMBL20828420 | 0.74 | DGAT1 (0.47) | DGAT1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL20828340 | 0.74 | BRAF (0.46) | DGAT1MCHR1 | |
| SCHEMBL20828421 | 0.73 | SCD (0.43) | DGAT1LMNASMN1; SMN2SLC2A1HDAC6 | |
| SCHEMBL20828418 | 0.73 | DGAT1 (0.44) | DGAT1SLC2A1 | |
| SCHEMBL20828385 | 0.73 | MAPT (0.54) | NPC1LMNARAB9AALDH1A1GLA | |
| SCHEMBL20828417 | 0.72 | ROCK2 (0.46) | DGAT1NPC1RAB9ASLC2A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |