Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828386 | 0.84 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAVCPKMT2A | |
| SCHEMBL5206947 | 0.76 | IDO1 (0.46) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL20828343 | 0.73 | DGAT1 (0.42) | ALDH1A1LMNARAB9AGLANPC1 | |
| SCHEMBL11068614 | 0.72 | KDM4E (0.49) | MAPTALDH1A1LMNAKMT2ARAB9A | |
| SCHEMBL26655923 | 0.71 | HTT (0.48) | ALDH1A1LMNAKMT2AMEN1GAA | |
| SCHEMBL16233111 | 0.71 | HPGD (0.34) | MAPTALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL2367956 | 0.69 | MEN1 (0.56) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL16197340 | 0.68 | CYP1A2 (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5078481 | 0.68 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL15244573 | 0.68 | KDM4C (0.34) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |