Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828305 | 0.80 | SIRT2 (0.37) | CETPIDO1SIRT2MEN1PKM | |
| SCHEMBL30234297 | 0.80 | SIRT2 (0.37) | CETPIDO1SIRT2MEN1PKM | |
| SCHEMBL30602664 | 0.80 | SIRT2 (0.37) | CETPIDO1SIRT2MEN1PKM | |
| SCHEMBL20828446 | 0.80 | MEN1 (0.44) | SIRT2MEN1KMT2AAURKARPS6KB1 | |
| SCHEMBL20828437 | 0.80 | MAPT (0.40) | MEN1PKMKMT2A | |
| SCHEMBL24721541 | 0.74 | RXRA (0.52) | CYP17A1PSMB8MAP4K4HDAC1 | |
| SCHEMBL20832631 | 0.71 | MAOA (0.44) | CETPSIRT2FFAR1 | |
| SCHEMBL12743181 | 0.70 | FADS1 (0.51) | CYP17A1IDO1MEN1KMT2AHDAC3 | |
| SCHEMBL20820812 | 0.70 | PPARG (0.43) | MEN1KMT2AJAK2 | |
| SCHEMBL20820811 | 0.70 | PPARG (0.43) | MEN1KMT2AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |