Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828305 | 1.00 | SIRT2 (0.37) | SIRT2MAPTRECQLALDH1A1LMNA | |
| SCHEMBL30234297 | 1.00 | SIRT2 (0.37) | SIRT2MAPTRECQLALDH1A1LMNA | |
| SCHEMBL20832880 | 0.90 | MAPT (0.46) | SIRT2MAPTRECQLALDH1A1POLB | |
| SCHEMBL20828522 | 0.86 | RAB9A (0.43) | MAPTPOLBMAPK1RORCKMT2A | |
| SCHEMBL20828436 | 0.80 | CYP17A1 (0.40) | SIRT2IDO1AURKARPS6KB1FFAR1 | |
| SCHEMBL30602672 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KMT2APKM | |
| SCHEMBL20828310 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KMT2APKM | |
| SCHEMBL20828311 | 0.76 | MET (0.37) | MAPTALDH1A1LMNAAURKARPS6KB1 | |
| SCHEMBL20832631 | 0.75 | MAOA (0.44) | SIRT2FFAR1RORCCETPPPARG | |
| SCHEMBL30602694 | 0.74 | IRAK4 (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094255-B | Compounds having cyclic structures | 第一三共株式会社 | 2023-10-03 | — | — | CN | disclosed |