Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828448 | 0.84 | MEN1 (0.42) | MEN1KMT2AROCK2ALDH1A1AURKA | |
| SCHEMBL20828435 | 0.80 | KMT2A (0.42) | MEN1KMT2AMAPTROCK2ALDH1A1 | |
| SCHEMBL20828446 | 0.80 | MEN1 (0.44) | MEN1KMT2AMAPTROCK2AURKA | |
| SCHEMBL20820116 | 0.79 | SLC2A1 (0.41) | MEN1KMT2AROCK2HPGDAURKA | |
| SCHEMBL20828442 | 0.77 | SLC2A1 (0.43) | MEN1KMT2AMAPTROCK2ALDH1A1 | |
| SCHEMBL20821325 | 0.75 | MAPT (0.53) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL20828365 | 0.74 | DGAT1 (0.47) | ROCK2SLC2A1CYP3A4 | |
| SCHEMBL20828403 | 0.70 | DGAT1 (0.41) | MAPTROCK2ALDH1A1KDM4ELMNA | |
| SCHEMBL20828341 | 0.69 | DGAT1 (0.48) | MEN1KMT2AMAPTROCK2TLR9 | |
| SCHEMBL20828420 | 0.68 | DGAT1 (0.47) | MEN1KMT2AMAPTROCK2TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |