Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | CBLB | Q13191 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828341 | 0.80 | DGAT1 (0.48) | DGAT1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20828446 | 0.79 | MEN1 (0.44) | MAPTSMN1; SMN2NPC1RAB9AROCK2 | |
| SCHEMBL20828420 | 0.79 | DGAT1 (0.47) | DGAT1MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL20828365 | 0.78 | DGAT1 (0.47) | DGAT1ROCK2CYP3A4CYP2C19 | |
| SCHEMBL20828417 | 0.77 | ROCK2 (0.46) | DGAT1MAPTNPC1RAB9AROCK2 | |
| SCHEMBL20828481 | 0.75 | FFAR1 (0.45) | DGAT1RAB9ACETPROCK2 | |
| SCHEMBL20828418 | 0.75 | DGAT1 (0.44) | DGAT1ROCK2 | |
| SCHEMBL20828401 | 0.74 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL20828421 | 0.73 | SCD (0.43) | DGAT1MAPTLMNASMN1; SMN2ROCK2 | |
| SCHEMBL30234297 | 0.70 | SIRT2 (0.37) | MAPTLMNASMN1; SMN2CETPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |