Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828420 | 0.92 | DGAT1 (0.47) | DGAT1SLC2A1HDAC6MEN1KMT2A | |
| SCHEMBL20828417 | 0.89 | ROCK2 (0.46) | DGAT1SLC2A1MEN1KMT2AROCK2 | |
| SCHEMBL20828418 | 0.85 | DGAT1 (0.44) | DGAT1SLC2A1MEN1KMT2AROCK2 | |
| SCHEMBL20828421 | 0.82 | SCD (0.43) | DGAT1SLC2A1HDAC6MEN1KMT2A | |
| SCHEMBL20820817 | 0.81 | DGAT1 (0.50) | DGAT1SLC2A1HDAC6ROCK2 | |
| SCHEMBL20828481 | 0.81 | FFAR1 (0.45) | DGAT1ROCK2RAB9A | |
| SCHEMBL20828403 | 0.80 | DGAT1 (0.41) | DGAT1ROCK2CYP3A4CYP2C19KDM4E | |
| SCHEMBL20828340 | 0.79 | BRAF (0.46) | DGAT1ROCK2 | |
| SCHEMBL20828451 | 0.79 | BRAF (0.44) | SLC2A1ROCK2RAB9A | |
| SCHEMBL20828342 | 0.79 | DGAT1 (0.58) | DGAT1SLC2A1HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |