Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 12/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828446 | 0.79 | MEN1 (0.44) | ROCK2CYP3A4SLC2A1 | |
| SCHEMBL20828403 | 0.78 | DGAT1 (0.41) | DGAT1ROCK2CYP3A4CYP2C19 | |
| SCHEMBL20828341 | 0.76 | DGAT1 (0.48) | DGAT1ROCK2CYP3A4CYP2C19SLC2A1 | |
| SCHEMBL20828366 | 0.76 | CYP3A4 (0.35) | DGAT1ROCK2CYP3A4CYP2C19ROCK1 | |
| SCHEMBL20828420 | 0.75 | DGAT1 (0.47) | DGAT1ROCK2CYP3A4CYP2C19SLC2A1 | |
| SCHEMBL20828448 | 0.74 | MEN1 (0.42) | ROCK2CYP3A4SLC2A1 | |
| SCHEMBL20828449 | 0.74 | MEN1 (0.42) | ROCK2CYP3A4SLC2A1 | |
| SCHEMBL20820817 | 0.74 | DGAT1 (0.50) | DGAT1ROCK2SLC2A1 | |
| SCHEMBL20828417 | 0.73 | ROCK2 (0.46) | DGAT1ROCK2SLC2A1 | |
| SCHEMBL20828342 | 0.72 | DGAT1 (0.58) | DGAT1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |