SCHEMBL20735229

SCHEMBL20735229

COc1ccc2c3c(ccc(-c4ccc(-c5ccncc5)cc4)c13)C(=O)N(c1ccccc1)C2=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
POLB P06746 1/20 0.51
KDM4E B2RXH2 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 1/20 0.44
NR1H3 Q13133 2/20 0.40
MCHR1 Q99705 1/20 0.40
NR1H2 P55055 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
ERN1 O75460 1/20 0.40
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
USP2 O75604 2/20 0.39
RAB9A P51151 1/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735130 0.88 ALDH1A1 (0.59) ALDH1A1POLBKDM4ESMN1; SMN2NR1H3
SCHEMBL20735178 0.87 ALDH1A1 (0.50) ALDH1A1POLBKDM4ESMN1; SMN2HPGD
SCHEMBL20735042 0.83 PRMT1 (0.50) ALDH1A1POLBKDM4EGABRA1GABRG2
SCHEMBL20735129 0.82 RAB9A (0.43) ALDH1A1POLBKDM4ESMN1; SMN2HPGD
SCHEMBL20735131 0.82 ALDH1A1 (0.50) ALDH1A1POLBKDM4ESMN1; SMN2NR1H3
SCHEMBL20735114 0.80 RAB9A (0.52) ALDH1A1POLBKDM4EHPGDNR1H3
SCHEMBL20735076 0.80 RAB9A (0.52) ALDH1A1POLBKDM4EHPGDNR1H3
SCHEMBL15267393 0.78 KDM4E (0.67) ALDH1A1POLBKDM4ESMN1; SMN2HPGD
SCHEMBL21481522 0.78 ALDH1A1 (0.57) ALDH1A1POLBKDM4ESMN1; SMN2HPGD
SCHEMBL20735073 0.77 KMT2A (0.58) ALDH1A1POLBKDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209862-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209862-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-11641754-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-02 US disclosed
US-11641754-B2 Organic light-emitting device and electronic apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-02 US disclosed
EP-3442047-B1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO LTD (KR) 2021-05-05 EP disclosed
US-10381596-B2 Organic light-emitting display apparatus with an encapsulation unit SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-13 US disclosed
US-20190051860-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-14 US disclosed
US-20190051856-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190051860-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS ALDH1A1, AOX1, ALDH1A2 ALDH1A1 1/4885POLB 3835/4885KDM4E 4393/4885
US-10381596-B2 Organic light-emitting display apparatus with an encapsulation unit ALDH1A1, AOX1, AMY1A ALDH1A1 1/4885POLB 3903/4885KDM4E 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.