Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 17/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701752 | 0.81 | TRPC5 (0.60) | TRPC5KCNH2TRPC4P2RX7 | |
| SCHEMBL20831543 | 0.77 | TRPC5 (0.52) | TRPC5KCNH2TRPC4 | |
| SCHEMBL20831375 | 0.76 | TRPC5 (1.00) | TRPC5KCNH2TRPC4ALDH1A1 | |
| SCHEMBL20817975 | 0.76 | TRPC5 (0.55) | TRPC5KCNH2TRPC4RAB9AMEN1 | |
| SCHEMBL25702140 | 0.73 | TRPC5 (0.42) | TRPC5MEN1KMT2ASMN1; SMN2P2RX7 | |
| SCHEMBL25698409 | 0.71 | CA12 (0.41) | TRPC5RAB9AKDM4EALDH1A1PLA2G1B | |
| SCHEMBL25708494 | 0.70 | TRPC5 (0.33) | TRPC5RAB9AMEN1POLBBLM | |
| SCHEMBL25701933 | 0.70 | ACHE (0.41) | TRPC5KCNH2TRPC4RAB9AKMT2A | |
| SCHEMBL20831621 | 0.69 | RAB9A (0.33) | RAB9AMEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL25703193 | 0.68 | TRPC5 (0.51) | TRPC5KCNH2TRPC4P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |