Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13272883 | 0.84 | NPC1 (0.73) | NPC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL20833638 | 0.83 | KMT2A (0.46) | NPC1RAB9ASMN1; SMN2POLBPKM | |
| SCHEMBL13845733 | 0.83 | RAB9A (0.50) | NPC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL13845690 | 0.77 | RPS6KA3 (0.50) | NPC1RAB9AHPGDSMN1; SMN2POLB | |
| SCHEMBL27117420 | 0.76 | HDAC1 (0.44) | NPC1RAB9AHDAC6HDAC1HDAC2 | |
| SCHEMBL20833587 | 0.75 | BRD4 (0.51) | NPC1RAB9AHDAC6HDAC2HDAC8 | |
| SCHEMBL20833871 | 0.75 | HPGD (0.55) | HDAC6HDAC2HDAC8HPGDSMN1; SMN2 | |
| SCHEMBL20833589 | 0.73 | HDAC1 (0.42) | NPC1RAB9AHDAC6HDAC1HDAC2 | |
| SCHEMBL5656075 | 0.72 | HDAC6 (0.71) | NPC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL26505437 | 0.72 | HDAC1 (0.53) | NPC1RAB9AHDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190084928-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING AROMATIC AMIDE, METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE, AND COMPOUND | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084928-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING AROMATIC AMIDE, METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE, AND COMPOUND | NIT2, NAAA, NOS2 | NPC1 4010/4885RAB9A 2440/4885HDAC6 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.