Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833587 | 0.83 | BRD4 (0.51) | HPGDALDH1A1BRD4POLBPKM | |
| SCHEMBL20527221 | 0.78 | ATR (0.47) | HPGDPOLBSMN1; SMN2HDAC2HDAC8 | |
| SCHEMBL20833658 | 0.75 | NPC1 (0.54) | HPGDBRD4POLBPKMSMN1; SMN2 | |
| SCHEMBL20833638 | 0.74 | KMT2A (0.46) | ALDH1A1BRD4POLBPKMSMN1; SMN2 | |
| SCHEMBL31276998 | 0.72 | PHGDH (0.62) | HPGDALDH1A1POLBPKMSMN1; SMN2 | |
| SCHEMBL27306159 | 0.70 | HPGD (0.62) | HPGDALDH1A1POLBPKMSMN1; SMN2 | |
| SCHEMBL2736608 | 0.70 | ALDH1A1 (0.59) | HPGDALDH1A1BRD4POLBHDAC2 | |
| SCHEMBL24498596 | 0.69 | BRD4 (0.51) | HPGDALDH1A1BRD4POLBPKM | |
| SCHEMBL13272883 | 0.69 | NPC1 (0.73) | BRD4HDAC2HDAC8HDAC6KMT2A | |
| SCHEMBL5743914 | 0.69 | ALDH1A1 (0.44) | HPGDALDH1A1SMN1; SMN2HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190084928-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING AROMATIC AMIDE, METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE, AND COMPOUND | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084928-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING AROMATIC AMIDE, METHOD FOR PRODUCING PYRROLE-IMIDAZOLE POLYAMIDE, AND COMPOUND | NIT2, NAAA, NOS2 | HPGD 687/4885ALDH1A1 2192/4885BRD4 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.