Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CTH | P32929 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19434684 | 0.90 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL19434681 | 0.90 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL21882639 | 0.82 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL17560761 | 0.80 | KMT2A (0.69) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL17560759 | 0.80 | KMT2A (0.69) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL16224338 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL17581319 | 0.76 | SMN1; SMN2 (0.57) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL17560913 | 0.74 | LMNA (0.66) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL17560916 | 0.74 | LMNA (0.66) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL19533016 | 0.74 | MAPT (0.66) | ALDH1A1MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190084941-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | NEOCULI PTY LTD (AU) | 2019-03-21 | — | — | US | disclosed |
| US-9327005-B1 | Compositions and methods for improved energy metabolism | VDF FUTURECEUTICALS, INC. (US) | 2016-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084941-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | ELANE, IL1A, IL1B | ALDH1A1 1016/4885MEN1 493/4885KMT2A 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.