Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837458 | 0.84 | HTR2A (0.47) | HTR2ASLC6A4KCNH2MAOAMAOB | |
| SCHEMBL16663979 | 0.79 | HTR2A (0.48) | HTR2ASLC6A4KCNH2MAOAMAOB | |
| SCHEMBL16663703 | 0.78 | HTR2A (0.43) | HTR2ASLC6A4KCNH2MAOAMAOB | |
| SCHEMBL26420789 | 0.76 | HPD (0.38) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL9450687 | 0.74 | XDH (0.43) | MMP14MAOAMAOBALDH1A1MAPT | |
| SCHEMBL7857224 | 0.74 | MMP14 (0.40) | HTR2ASLC6A4KCNH2MMP14MAOA | |
| SCHEMBL12874169 | 0.73 | IDO1 (0.60) | SLC6A4MAOBALDH1A1 | |
| SCHEMBL8476320 | 0.73 | HTR2A (0.40) | HTR2ASLC6A4KCNH2MAOAMAOB | |
| SCHEMBL28659130 | 0.70 | HTR2A (0.50) | HTR2ASLC6A4KCNH2MAOAMAOB | |
| SCHEMBL2093599 | 0.70 | PYCR1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3059224-B1 | 4-AMINOMETHYLBENZOIC ACID DERIVATIVE | TOA EIYO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |