Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20838507 | 0.79 | NFKBIA (0.53) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL11544441 | 0.76 | KMT2A (0.51) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL5445828 | 0.73 | HSP90AA1 (0.62) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL15561143 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL11864603 | 0.67 | CYP3A4 (0.41) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL16960151 | 0.66 | ALDH1A1 (0.46) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL28935509 | 0.66 | MEN1 (0.35) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL30019384 | 0.66 | MEN1 (0.35) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL30873750 | 0.66 | PDE10A (0.55) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL11201388 | 0.66 | MAPK1 (0.62) | LMNAALDH1A1HPGDCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466931-B1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | UNIV GUANGDONG TECHNOLOGY (CN) | 2024-01-10 | — | — | EP | disclosed |
| US-10807957-B2 | Tetradentate chelating monoquinoline derivative, manufacturing method thereof, and application of same as metal ion regulator for neurodegenerative disease | UNIV GUANGDONG TECHNOLOGY (CN) | 2020-10-20 | — | — | US | disclosed |
| EP-3466931-A1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | Guangdong University Of Technology (CN) | 2019-04-10 | — | — | EP | disclosed |
| US-20190092730-A1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | GUANGDONG UNIVERSITY OF TECHNOLOGY | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807957-B2 | Tetradentate chelating monoquinoline derivative, manufacturing method thereof, and application of same as metal ion regulator for neurodegenerative disease | SOD1, SLC30A6, SLC30A7 | MEN1 1818/4885KMT2A 1151/4885LMNA 4524/4885 |
| US-20190092730-A1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | SOD1, SLC30A6, SLC30A7 | MEN1 1818/4885KMT2A 1151/4885LMNA 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.