Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 5/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855995 | 1.00 | CRHR1 (0.34) | CRHR1ABL1ARTLR7 | |
| SCHEMBL22380778 | 0.90 | ABL1 (0.36) | ABL1TLR7 | |
| SCHEMBL22380822 | 0.83 | IDH1 (0.33) | ABL1 | |
| SCHEMBL19406779 | 0.81 | TLR7 (0.38) | CRHR1ABL1ARTLR7 | |
| SCHEMBL22372368 | 0.80 | ABL1 (0.34) | ABL1TLR7 | |
| SCHEMBL20845420 | 0.76 | ABL1 (0.32) | ABL1TLR7 | |
| SCHEMBL29856022 | 0.76 | MAPK14 (0.33) | ABL1TLR7 | |
| SCHEMBL20839198 | 0.76 | MAPK14 (0.33) | ABL1TLR7 | |
| SCHEMBL25611201 | 0.75 | TLR7 (0.32) | ABL1TLR7 | |
| SCHEMBL20845417 | 0.74 | ABL1 (0.34) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| EP-3684182-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| EP-3684182-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| EP-3684182-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019057720-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057720-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | PLPBP, PDXK, DPYD | CRHR1 4836/4885ABL1 642/4885AR 4814/4885 |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | PLPBP, PDXK, DPYD | CRHR1 4836/4885ABL1 642/4885AR 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.