Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 4/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20849505 | 0.86 | S1PR1 (0.37) | IDH1CYP11B2CYP11B1NPSR1HTT | |
| SCHEMBL22380778 | 0.85 | ABL1 (0.36) | ABL1CYP3A4 | |
| SCHEMBL29855995 | 0.83 | CRHR1 (0.34) | ABL1 | |
| SCHEMBL20839396 | 0.83 | CRHR1 (0.34) | ABL1 | |
| SCHEMBL20845417 | 0.82 | ABL1 (0.34) | IDH1ABL1 | |
| SCHEMBL22372368 | 0.80 | ABL1 (0.34) | CYP11B2ABL1CYP2C9CYP2C19 | |
| SCHEMBL20853046 | 0.80 | HDAC1 (0.35) | ABL1 | |
| SCHEMBL20839164 | 0.78 | NQO2 (0.34) | IDH1CYP11B2PIM1CYP11B1NPSR1 | |
| SCHEMBL20839156 | 0.78 | CYP11B2 (0.38) | CYP11B2CYP11B1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL30014252 | 0.78 | CYP11B2 (0.38) | CYP11B2CYP11B1NPSR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-13 | — | — | US | disclosed |
| EP-3684182-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200267981-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrimidine Derivatives | PLPBP, PDXK, DPYD | IDH1 48/4885CYP11B2 2262/4885PIM1 2030/4885 |
| US-11672251-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrimidine derivatives | PLPBP, PDXK, DPYD | IDH1 48/4885CYP11B2 2262/4885PIM1 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.