Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dectaflur. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.61 |
| ▸ | TERT | O14746 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | PPARD | Q03181 | 3/20 | 0.60 |
| ▸ | PPARA | Q07869 | 3/20 | 0.60 |
| ▸ | TOP1 | P11387 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dectaflur SCHEMBL208407 | 1.00 | SLC6A5 (0.61) | SLC6A5TERTPTPN1PPARGPPARD | |
| Dectaflur SCHEMBL326025 | 1.00 | SLC6A5 (0.61) | SLC6A5TERTPTPN1PPARGPPARD | |
| Dectaflur SCHEMBL326023 | 1.00 | SLC6A5 (0.61) | SLC6A5TERTPTPN1PPARGPPARD | |
| Acetic Acid SCHEMBL29763760 | 0.94 | ALDH1A1 (0.64) | SLC6A5PPARGPPARDPPARAMAPT | |
| Dectaflur SCHEMBL30785506 | 0.94 | SLC6A5 (0.63) | SLC6A5TERTPTPN1PPARGPPARD | |
| Dectaflur SCHEMBL28526908 | 0.92 | FAAH (0.66) | SLC6A5TERTPTPN1PPARGPPARD | |
| Dectaflur SCHEMBL28329553 | 0.92 | SLC6A5 (0.61) | SLC6A5TERTPTPN1PPARGPPARD | |
| Oleamide SCHEMBL326024 | 0.91 | FAAH (0.77) | SLC6A5TERTPTPN1PPARGPPARD | |
| Dectaflur SCHEMBL9009549 | 0.90 | TERT (0.63) | SLC6A5TERTPTPN1PPARGPPARD | |
| Dectaflur SCHEMBL9009554 | 0.90 | TERT (0.63) | SLC6A5TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4160804-B1 | COATED SEPARATOR FOR LITHIUM ION BATTERY AND METHOD FOR PREPARING SAME | JIANGSU HORIZON NEW ENERGY TECH CO LTD (CN) | 2024-04-24 | — | — | EP | claimed |
| EP-4160804-A1 | COATED SEPARATOR FOR LITHIUM ION BATTERY AND METHOD FOR PREPARING SAME | Jiangsu Horizon New Energy Tech Co., Ltd (CN) | 2023-04-05 | — | — | EP | claimed |
| CN-107384569-B | Method for continuously recycling waste lubricating oil without pollution | 广州世洁环保服务有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-110530857-A | A kind of high sensitivity oxygen indicator and preparation method thereof | NANJING TIANHUA TECH DEVELOPMENT CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-107134297-B | A kind of insulation box for instrument of high antiseptic property | 扬中市众成管路配件有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-107201145-B | A kind of sub-nanometer ball-shaped silicon micro powder enhancing water paint | 苏州吉云新材料技术有限公司 | 2019-09-10 | — | — | CN | claimed |
| CN-109852102-A | A kind of preparation method of bloom BOPP biaxially oriented film specialized superfine calcium carbonate | 江西广源化工有限责任公司 | 2019-06-07 | — | — | CN | claimed |
| CN-109370508-A | A kind of radiation-curable black shading Adhesive composition | 东莞市联灏新材料技术开发有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-109135512-A | A kind of building template release coating | 武汉掌声科技有限责任公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108774426-A | A kind of high performance surface attachment ink and preparation method thereof | 南雄市科鼎化工有限公司 | 2018-11-09 | — | — | CN | claimed |
| CN-101928000-B | Purification method of high-purity sub-nanometer silicon carbide micro powder | ZHONG PING ENERGY CHEMICAL GROUP YICHENG NEW MATERIAL CO LTD | 2012-07-04 | — | — | CN | claimed |
| CN-102241914-A | Water-based UV (ultraviolet) ink and preparation method thereof | UNIV XIAN TECHNOLOGY | 2011-11-16 | — | — | CN | claimed |
| CN-101928000-A | Purification method of high-purity sub-nanometer silicon carbide micro powder | ZHONG PING ENERGY CHEMICAL GROUP YICHENG NEW MATERIAL CO LTD | 2010-12-29 | — | — | CN | claimed |
| CN-101892008-A | Water-based electric heating coating and use thereof | PEI WANG | 2010-11-24 | — | — | CN | claimed |
| CN-100339442-C | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2007-09-26 | — | — | CN | claimed |
| US-20050049316-A1 | Emulsified water fuel blend containing an aqueous organic ammonium salt | BURRINGTON JAMES D (US) | 2005-03-03 | — | — | US | claimed |
| CN-1569968-A | Yellow, orange benzimidazolone like azo dye making method | UNIV EAST CHINA SCIENCE & TECH (CN) | 2005-01-26 | — | — | CN | claimed |
| CN-1563202-A | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2005-01-12 | — | — | CN | claimed |
| US-20040020105-A1 | Emulsified water fuel blend containing an aqueous organic ammonium salt | THE LUBRIZOL CORPORATION A CORPORATION OF THE STATE OF OHIO | 2004-02-05 | — | — | US | claimed |
| US-4331572-A | Efficient synthetic thickener composition | AMERICAN HOECHST CORPORATION (US) | 1982-05-25 | — | — | US | claimed |