SCHEMBL20844261

SCHEMBL20844261

CCCCc1ccc2c(c1)c1cc(CCCC)ccc1n2C(C)(CC)CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 2/20 0.43
RORC P51449 2/20 0.43
RORB Q92753 2/20 0.43
SKP2 Q13309 1/20 0.40
HTR1A P08908 2/20 0.38
DHFR P00374 1/20 0.37
PGR P06401 2/20 0.37
HPGD P15428 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTR1D P28221 1/20 0.34
HTR1B P28222 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20844239 0.93 RORA (0.47) RORARORCRORBPGRHPGD
SCHEMBL12083618 0.78 KDM4E (0.51) RORARORCRORBSKP2HTR1A
SCHEMBL25922519 0.76 RORA (0.47) RORARORCRORBSKP2HTR1A
SCHEMBL23045923 0.75 RORA (0.37) RORARORCRORBSKP2HTR1A
SCHEMBL20844244 0.74 RORA (0.39) RORARORCRORBDHFRPGR
SCHEMBL13564047 0.72 RORA (0.47) RORARORCRORBSKP2HTR1A
SCHEMBL13616802 0.71 RORA (0.59) RORARORCRORBHTR1AHPGD
SCHEMBL13932483 0.71 UCHL3 (0.43) RORARORCRORBSKP2HTR1A
SCHEMBL12083703 0.71 RORC (0.56) RORARORCRORBPGRHPGD
SCHEMBL28409215 0.70 RORA (0.51) RORARORCRORBPGRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3622569-B1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT CYNORA GMBH (DE) 2021-08-11 EP disclosed
EP-3622568-B1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT CYNORA GMBH (DE) 2021-08-11 EP disclosed
EP-3401971-B1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING BLUE LIGHT CYNORA GMBH (DE) 2019-03-27 EP disclosed
EP-3401972-B1 BLUE LIGHT EMITTING ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-03-27 EP disclosed