Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23221828 | 0.88 | ADAM10 (0.39) | LTA4HADAM10MMP2MMP9MMP12 | |
| SCHEMBL19633304 | 0.86 | SPHK1 (0.41) | LTA4HSPHK1ADAM10MMP2MMP9 | |
| SCHEMBL17469339 | 0.86 | LTA4H (0.48) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL19155027 | 0.86 | LTA4H (0.48) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL16925763 | 0.84 | LTA4H (0.64) | LTA4HSPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL21849119 | 0.84 | LTA4H (0.47) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL21208111 | 0.84 | LTA4H (0.47) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL16645072 | 0.84 | LTA4H (0.47) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL25100491 | 0.83 | LTA4H (0.46) | LTA4HSPHK1SPHK2ANPEPS1PR1 | |
| SCHEMBL17801791 | 0.83 | SPHK1 (0.51) | LTA4HSPHK1SPHK2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019060398-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-28 | — | — | WO | disclosed |