Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686640 | 0.85 | NOTUM (0.35) | NOTUM | |
| SCHEMBL18871241 | 0.82 | PDK2 (0.33) | SLC6A2SLC6A4SLC6A3PDK2PDK4 | |
| SCHEMBL21317950 | 0.82 | NOTUM (0.32) | NOTUM | |
| SCHEMBL22563926 | 0.80 | NOTUM (0.36) | NOTUMSLC6A2SLC6A4SLC6A3PDK2 | |
| SCHEMBL18831572 | 0.79 | LMNA (0.33) | — | |
| SCHEMBL18831729 | 0.79 | HPGD (0.31) | — | |
| SCHEMBL23678166 | 0.79 | — | — | |
| SCHEMBL20686703 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL20686632 | 0.78 | GABRA1 (0.34) | — | |
| SCHEMBL18831732 | 0.78 | HTT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029038-B1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-03-27 | — | — | EP | disclosed |