Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839273 | 0.88 | CYP11B2 (0.38) | PIM1CYP11B2PIK3CGCYP11B1ABL1 | |
| SCHEMBL29911053 | 0.84 | PIM1 (0.42) | PIM1CYP11B2CYP11B1PARP10PARP11 | |
| SCHEMBL20839010 | 0.84 | PIM1 (0.42) | PIM1CYP11B2CYP11B1PARP10PARP11 | |
| SCHEMBL20839344 | 0.83 | TLR7 (0.34) | PIM1ABL1HCRTR1HCRTR2 | |
| SCHEMBL24013138 | 0.83 | PIM1 (0.34) | PIM1CYP11B2PIK3CGCYP11B1ABL1 | |
| SCHEMBL20843700 | 0.80 | TLR7 (0.40) | ABL1 | |
| SCHEMBL20839266 | 0.77 | TLR7 (0.34) | PIM1CYP11B2ABL1HCRTR1HCRTR2 | |
| SCHEMBL20846011 | 0.75 | PIK3CG (0.46) | PIM1CYP11B2PIK3CGCYP11B1ABL1 | |
| SCHEMBL20839264 | 0.75 | CYP11B2 (0.36) | PIM1CYP11B2PIK3CGCYP11B1ABL1 | |
| SCHEMBL20839015 | 0.72 | PIM1 (0.43) | PIM1CYP11B2CYP11B1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-20 | — | — | US | disclosed |
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-20 | — | — | US | disclosed |
| EP-3684764-B1 | PYRAZINE-4-CARBAMATE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-10 | — | — | EP | disclosed |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| WO-2019057724-A1 | PYRAZINE-4CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | DDT, PLPBP, CPS1 | PIM1 1335/4885CYP11B2 3239/4885PIK3CG 926/4885 |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | PLPBP, PDXK, HPD | PIM1 1700/4885CYP11B2 3269/4885PIK3CG 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.