Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 11/20 | 1.00 |
| ▸ | MEN1 | O00255 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | GAA | P10253 | 6/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | NSD2 | O96028 | 2/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 1.00 |
| ▸ | NPY2R | P49146 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 5/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403957 | 0.79 | HSPD1 (0.81) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2403963 | 0.79 | HSPD1 (0.81) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2403960 | 0.79 | HSPD1 (0.81) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2492218 | 0.77 | MEN1 (0.74) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL14788065 | 0.77 | MEN1 (0.74) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2492219 | 0.77 | MEN1 (0.74) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5284210 | 0.76 | HSD17B3 (0.78) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL14788079 | 0.76 | HSPD1 (0.64) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5284212 | 0.76 | HSD17B3 (0.78) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2532230 | 0.76 | HSPD1 (0.64) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165815-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER?S DISEASE | Lu, Qun (US) | 2023-06-01 | — | — | US | disclosed |
| US-20190091184-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER'S DISEASE | LU, QUN | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165815-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER?S DISEASE | CDC42, MDN1, GAP43 | MAPT 267/4885KMT2A 4297/4885MEN1 3675/4885 |
| US-20190091184-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER'S DISEASE | CDC42, MDN1, HASPIN | MAPT 326/4885KMT2A 4371/4885MEN1 3739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.