Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167257 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10HDAC4HDAC6 | |
| SCHEMBL2148474 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL7432060 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL15282179 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10HDAC4HDAC6 | |
| SCHEMBL9068703 | 0.77 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10HDAC4HDAC6 | |
| SCHEMBL12523450 | 0.76 | THRB (0.35) | ALDH1A1LMNAHSD17B10HDAC4HDAC6 | |
| SCHEMBL23473944 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10HDAC4HDAC6 | |
| SCHEMBL196658 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10HDAC4HDAC6 | |
| SCHEMBL1770642 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10HDAC4HDAC6 | |
| SCHEMBL3908512 | 0.74 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057720-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |