SCHEMBL20848600

SCHEMBL20848600

Cn1c2ccccc2c2cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)ccc21

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.60
GPR3 P46089 1/20 0.48
NPY5R Q15761 1/20 0.47
KDM4E B2RXH2 2/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ICMT O60725 7/20 0.42
RXRA P19793 2/20 0.41
RXRB P28702 2/20 0.41
PGR P06401 1/20 0.41
NR1H3 Q13133 1/20 0.41
PABPC1 P11940 1/20 0.39
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16848587 0.84 GPR3 (0.64) KIF11GPR3NPY5RKDM4EMAPT
SCHEMBL13086784 0.84 GPR3 (0.64) KIF11GPR3NPY5RKDM4EMAPT
SCHEMBL10331500 0.83 GPR3 (0.70) KIF11GPR3NPY5RKDM4EMAPT
SCHEMBL10447275 0.83 GPR3 (0.70) KIF11GPR3NPY5RKDM4EMAPT
SCHEMBL21454579 0.82 KIF11 (0.81) KIF11GPR3NPY5RKDM4EMAPT
SCHEMBL17809439 0.82 GPR3 (0.67) KIF11GPR3NPY5RKDM4EMAPT
SCHEMBL21738790 0.80 ICMT (0.39) KIF11NPY5RMEN1KMT2AICMT
SCHEMBL12419782 0.80 GPR3 (0.64) KIF11GPR3NPY5RKDM4EMAPT
SCHEMBL16710489 0.80 KIF11 (0.43) KIF11KDM4EL3MBTL1ALDH1A1ICMT
SCHEMBL21116285 0.79 ICMT (0.39) KIF11KDM4EL3MBTL1ICMTRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190097141-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OCIAD2, OCIAD1, POU2F1 KIF11 419/4885GPR3 3205/4885NPY5R 4191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.