SCHEMBL21116285

SCHEMBL21116285

FC(F)(F)c1cc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3ccc(C(F)(F)F)c(-n4c5ccccc5c5cc(-c6cc(C(F)(F)F)cc(C(F)(F)F)c6)ccc54)c3)ccc2C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ICMT O60725 9/20 0.39
KIF11 P52732 1/20 0.38
TACR1 P25103 3/20 0.34
RXRA P19793 2/20 0.33
RXRB P28702 2/20 0.33
HSP90AA1 P07900 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
RXRG P48443 1/20 0.33
PTGES O14684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21116561 0.93 ICMT (0.38) ICMTKIF11RXRARXRBHSP90AA1
SCHEMBL21116283 0.92 KIF11 (0.40) ICMTKIF11TACR1RXRARXRB
SCHEMBL21116889 0.91 KIF11 (0.41) KIF11HSP90AA1KDM4EATML3MBTL1
SCHEMBL21116900 0.89 KIF11 (0.46) KIF11HSP90AA1KDM4EATML3MBTL1
SCHEMBL21116344 0.88 TSPO (0.40) KIF11RXRARXRBKDM4EATM
SCHEMBL26534941 0.86 ICMT (0.40) ICMTRXRARXRBKDM4EL3MBTL1
SCHEMBL21131432 0.86 ICMT (0.37) ICMTKIF11TACR1RXRARXRB
SCHEMBL21116492 0.85 L3MBTL1 (0.40) KIF11KDM4EATML3MBTL1PTGES
SCHEMBL21116489 0.85 L3MBTL1 (0.40) KIF11KDM4EATML3MBTL1PTGES
SCHEMBL21116284 0.85 RXRA (0.37) ICMTKIF11RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136294-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-10-05 US disclosed
US-20190194130-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194130-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, NOX3, ORC3 ICMT 2503/4885KIF11 3544/4885TACR1 1273/4885
US-11136294-B2 Organic molecules for use in optoelectronic devices OR10J3, ORC3, NOX3 ICMT 2637/4885KIF11 3520/4885TACR1 1146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.