SCHEMBL20850233

SCHEMBL20850233

CC1(C)c2cc(N(c3ccccc3)c3ccc(-c4ccccc4)nc3)ccc2-c2sc(C=C(C#N)C#N)cc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ APP P05067 1/20 0.33
▸ CYP11B1 P15538 1/20 0.30
▸ SLC16A3 O15427 1/20 0.30
▸ SLC16A1 P53985 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850395 0.89 MAPT (0.37) MEN1KMT2AMAPTAPPSLC16A3
SCHEMBL20850098 0.89 SLC16A3 (0.36) MEN1KMT2AMAPTAPPSLC16A3
SCHEMBL20850391 0.88 MAPT (0.36) MEN1KMT2AMAPTAPPSLC16A3
SCHEMBL20850284 0.85 SLC16A3 (0.34) MEN1KMT2AMAPTAPPSLC16A3
SCHEMBL20850288 0.85 MAPT (0.34) MEN1KMT2AMAPTAPPSLC16A3
SCHEMBL20850232 0.85 APP (0.31) MEN1KMT2AAPP
SCHEMBL20850283 0.84 SLC16A3 (0.33) MEN1KMT2AMAPTAPPSLC16A3
SCHEMBL20850389 0.83 SLC16A3 (0.32) MEN1KMT2AMAPTAPPSLC16A3
SCHEMBL20850299 0.82 MAPT (0.32) MAPTAPP
SCHEMBL20850286 0.81 MAPT (0.34) MEN1KMT2AMAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 MEN1 3080/4885KMT2A 2556/4885MAPT 3800/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 MEN1 3080/4885KMT2A 2556/4885MAPT 3800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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