SCHEMBL20850382

SCHEMBL20850382

CC1(C)c2cc(N(c3ccccc3)c3cc4ccccc4s3)cnc2-c2sc(C=C3C(=O)c4ccccc4C3=O)cc21

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ GSK3B P49841 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850125 0.90 ALDH1A1 (0.37) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850379 0.87 ALDH1A1 (0.31) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850281 0.86 ALDH1A1 (0.32) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850234 0.86 ALDH1A1 (0.33) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850380 0.84 ALDH1A1 (0.30) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850431 0.83 ALDH1A1 (0.31) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850352 0.83 ALDH1A1 (0.31) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850356 0.83 ALDH1A1 (0.37) ALDH1A1MAPTTHRBHPGDRECQL
SCHEMBL20850443 0.83 — —
SCHEMBL20850323 0.83 MAOA (0.33) ALDH1A1MAPTTHRBHPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 ALDH1A1 602/4885MAPT 3800/4885THRB 2050/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 ALDH1A1 602/4885MAPT 3800/4885THRB 2050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback